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Recent advances in microbiology have led to the recognition of the gut microbiota as an essential component contributing to the aging process. The gut microbiota is a diverse ecosystem of microorganisms residing in the gastrointestinal tract that profoundly influences host health. This journal entry aims to explore the mechanisms by which the gut microbiota influences aging and potential interventions for healthier aging, drawing on relevant scientific literature. Gut Microbiota Composition a...

Introduction Longevity, the desire to extend our lifespan while preserving health and vitality, has been a fascination throughout human history. In the quest for longevity, medical science has made significant strides, unveiling the roles of cellular processes, senescent cells, mitochondrial function, and telomere health in the aging process. Alongside these breakthroughs, natural compounds have emerged as promising contenders in supporting healthy aging. This article delves into the cellular...

L-ergothioneine is a naturally occurring amino acid derivative that accumulates within cells, particularly in mitochondria. Mitochondria are cellular organelles known as the powerhouses of the cell, responsible for generating energy in the form of adenosine triphosphate (ATP) through oxidative phosphorylation. The accumulation of L-ergothioneine within the mitochondria is due to a specific transporter protein known as OCTN1 (organic cation/carnitine transporter 1). This transporter is respons...